Chemicals
EFF-Pharm: Effects of pharmaceuticals (nonsteroidal anti-inflammatory drugs and beta-blockers) in fish and invertebrates and their detection by newly developed in vitro-bioassays
As tools for environmental monitoring of pharmaceuticals, mode of action -based in vitro-assays were developed for beta-blockers as metoprolol, and non-steroidal anti-inflammatory drugs, as diclofenac. In order to validate these tests for their suitability to reflect in vivo-effects in aquatic organisms, toxicity tests and biomarker studies were conducted with fish, crustaceans, snails and sedimen…weiterlesen