Cover Texte 48/2014 Review and Enhancement of New Risk Assessment Concepts under REACH
Chemicals

Review and Enhancement of New Risk Assessment Concepts under REACH


In this project, the guidance documents should be verified using the example of potentially endocrine disrupting (ED) chemicals. Three substances were selected mainly based on in silico (2,4,6-tribromophenol), in vitro (benzanthrone) and in vivo data (benzophenone-2). In order to evaluate the potential for endocrine disruption, several additional in vitro tests and one in vivo test were performed for two of the selected substances. For all three selected substances, an integrated assessment of potential endocrine activity in aquatic vertebrates was performed. Results of this assessment are presented in a non-public annex to this report.

Series
Texte | 48/2014
Number of pages
150
Year of publication
Author(s)
Dr. Dietmar Warnecke, Dr. Karen Duis, Dr. Thomas Knacker, Prof. Dr. Gerrit Schüürmann, Dr. Ralph Kühne, Norbert Ost
Language
Englisch
Project No. (FKZ)
3708 65 407
Publisher
Umweltbundesamt
File size
1421 KB
Price
0,00 €
Print version
not available
rated as helpful
343
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 REACH  chemicals  chemical risk