Publikation:Quantitative biokinetic analysis of radioactively labelled, inhaled Titanium dioxide Nanoparticles in a rat model
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Quantitative biokinetic analysis of radioactively labelled, inhaled Titanium dioxide Nanoparticles in a rat model


The aim of this project was the determination of the biokinetics of TiO2 nanoparticles (NP) in the whole body of healthy adult rats after NP administration to the respiratory tract – either via inhalation or instillation. Here we offered applying our previously developed methodology of quantitative biokinetics using radio-labelled NP. Quantitative biokinetics means that not only the NP absolute contents and concentrations of NP in primary and secondary organs and tissues of interest are determined but also those of the remaining body (carcass) and those in faecal and urinary excretion. 

Series
Umwelt & Gesundheit | 04/2010
Number of pages
34
Year of publication
Author(s)
Wolfgang G. Kreyling, Alexander Wenk, Manuela Semmler-Behnke
Language
English
Project No. (FKZ)
3707 61 301/01
Publisher
Umweltbundesamt
File size
2940 KB
Price
0,00 €
Print version
not available
rated as helpful
268
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Tags:
 titanium dioxide nanoparticle  analysis  rat model  radioactively labelled