Cover_TEXTE_150-2020_Do new generations of active pharmaceuticals for human use require an adaption of the environmental risk assessment
Chemicals

Do new generations of active pharmaceuticals for human use require an adaption of the environmental risk assessment?, Part I: Literature review


Since 2006, various new active pharmaceutical ingredients have been developed with highly specific mechanisms of action. That raise the question of whether current environmental risk assessment within the scope of the authorization is still sufficient to appropriately assess relevant effects on environmental organisms. In this literature review the scientific basis for a tailored risk assessment was developed and discussed for 3 substance classes (oncology, neurology, cardiology). The proposed assessment includes additional test methods, groups of organisms and alternative endpoints. The practical review of the proposed test approaches is to be carried out using case studies in subproject 2.

Series
Texte | 150/2020
Number of pages
106
Year of publication
Author(s)
Dr. Manfred Kohler, Sebastian Stix, Dr. Björn Windshügel, Oliver Keminer, Azora König, Dr. Lena Kosak, Dr. Elke Eilebrecht
Language
English
Project No. (FKZ)
3718 65 420 1
Publisher
Umweltbundesamt
Additional information
PDF is accessible
File size
2222 KB
Price
0,00 €
Print version
not available
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