Standardisation of methods regarding fate and behaviour of nanomaterials in environmental media – solubility and dissolution rate
Dispersion stability, dissolution (rate) and transformation are considered as most important parameters influencing fate and behavior of nanomaterials in the environment. While there already is a standardized test guideline to establish data on dispersion stability, and while a guidance document on transformation of nanomaterials is underway, a standardized method to determine solubility and dissolution rate of nanomaterials under environment relevant conditions is still missing.
The objective of the project is to develop a working protocol which will include measurements under static and dynamic conditions in order to determine solubility and dissolution rate of nanomaterials under environmental relevant conditions. It is intended to submit the working protocol at OECD level to pursue the adoption as new OECD test guideline. (UFORDAT No. 01080733)
OECD Test Guideline development for nanomaterials: Transformation of nanomaterials under environmental conditions
In addition to their agglomeration (dispersion stability) and dissolution, whether and how nanomaterials are transformed over time via abiotic processes is also important for their behaviour and fate in the environment. This knowledge is significant to understand in which form and amount engineered nanomaterials are present in the environment. The research project aims to develop an OECD test guideline for a quantitative determination of the abiotic transformation processes of nanomaterials, taking into account relevant environmental parameters. The work builds on ongoing activities for the development of an OECD Guidance Document on environmental abiotic transformation of nanomaterials.
In addition, the project will also include investigations to validate a possible test protocol for determining the heteroagglomeration of nanomaterials under consideration of relevant environmental parameters. The basis for this will be the existing OECD test guideline 318 for the determination of dispersion stability of nanomaterials under environmental conditions, which is currently limited to the investigation of homoagglomeration of nanomaterials. (UFORDAT No. 01088269)
UBA participation in third-party funded projects
UBA is part of the advisory board to the EU Horizon 2020 Coordination and Support Action (CSA) “Nanoharmony”. “Nanoharmony” collects data and information in order to build the scientific basis for the development of new test methods for investigating nanomaterials in a close cooperation with OECD. UBA supports the cooperation in relation to environmental aspects in the view of a competent regulatory authority.