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AEGL - Acute Exposure Guideline Levels: Organization

The AEGL development process

Table of contents

How are AEGL values established ?

Initiated by the German „Federal Environmental Agency“, the „Hazardous Incident Commission“ („Störfallkommission“, now the „Kommission für Anlagensicherheit“, „Commission for Plant Safety“) is engaged in topics relating to hazardous incident guidance values since 1993. In the same year, guidelines were published in the USA which led to the AEGL values (more).

A German „Toxicology Expert Group“ of the „Commission for Plant safety“ („Kommission für Anlagensicherheit“, the former „Störfallkommission“) was established in 1999 which recommends toxicologically substantiated AEGL values (more on the national process of AEGL development).

Internationally there is close collaboration with the USA where national AEGL values are established (more on the process of AEGL development in the USA). The adoption of values agreed upon in the USA is not binding in Germany. Modifications may take place.

Within the OECD there are similar activities, especially in the Netherlands an France.

The history of AEGL values

First activities relating to hazardous incident guidance values in Germany date back to the late 80ies and early 90ies:

  • An (unpublished) concept for the derivation of „Störfallbeurteilungswerte“ was developed by the „Association of the Chemical Industry“ (Verband der Chemischen Industrie; VCI) around 1990.
  • In 1991, the „European Centre for Ecotoxicology and Toxicology of Chemicals“ (ECETOC) published a corresponding methodology.
  • The „Hazardous Incident Commission“ is engaged in this field since 1993 (and became the "Commission for Plant Safety", "Kommission für Anlagensicherheit", in 2005). It published a documentation of the respective international values in 1996 and initially developed draft values according to the ERPG concept (see below).
  • The „Federal Environmental Agency“ in cooperation with the federal states developed a list of priority substances relating to the Hazardous Incident Ordinance in 1994. For chemicals of this list assessment criteria should be established because of their relevance in relation to hazardous incidents.
  • Under contract of the „Federal Agency for Civil Defense“ the Technical University in Munich derived the so-called „Einsatztoleranzwerte“ in 1995/6.
  • The „Federal Environmental Agency“ charged the Research and Advisory Institute for Hazardous Substances (FoBiG) in Freiburg with the development of AEGL values in 1998. This was to be carried out in international collaboration after the former Hazardous Incident Commission adopted this concept and the Toxicology Expert Group was established.
  • Additional substances were covered by FoBiG and consultants Dr. Voß/Dr. Rosner within the framework of a follow-up project.

In the USA, considerations dating back to 1944 were taken up in the 70ies and led to initial hazardous incident reference values. In 1987, the „Emergency Response Planning Guideline Committee“ was set up which developed ERPG values still relevant in the USA and internationally. The National Research Council published a report entitled „Guidelines for Developing Community Emergency Exposure Levels for Hazardous Substances“ in 1993. The AEGL concept was then developed from the general methodological outlines of this report and the experiences gathered during derivation of ERPG values. It is planned to provide AEGL values for some 400 to 500 chemicals during the next ten years.

The OECD with its „Chemical Accidents Programme“ began to support AEGL values as well and, for example, dealt with it in two sessions (27th and 29th Joint Meeting of the Chemicals Group and Management Committee, Paris, 1998 and 1999).

Associated content

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SBW - Störfallbeurteilungswerte

Early in the 1990ies the German Association of the Chemical Industry (Verband der chemischen Industrie, VCI) produced an unpublished "Concept for the establishment of hazardous incident assessment values".
These values refer to an exposure period of 60 minutes and the level of severity is defined as generally not leading to life-threatening or severe and irreversible effects. Compared to ERPG these values usually lie between ERPG-2 and ERPG-3. It is noted in the concept that the values should be reviewed with regard to advancements in the methodology and recent data.

EEI - Emergency Exposure Indices

The "European Centre for Ecotoxicology and Toxicology of Chemicals" (ECETOC) of the European chemical industry provided a contribution to the derivation of hazardous incident values with its "Technical Report No. 43" entitled "Emergency Exposure Indices for Industrial Chemicals". Apart from two exemplary chemicals, however, no further values have been derived. While there are some differences in the definition of the severity levels, the procedure is by and large similar to the AEGL concept. By analogy to the AEGL concept, values for different exposure periods (e.g. 15, 30 and 60 minutes) could be established.

ETW - Einsatztoleranzwerte

The derivation of these values was carried out at the Technical University of Munich under contract for the Federal Agency for Civil Defense (Bundesamt für Zivilschutz) in 1995/6. These values are included in a draft guideline on hazardous concentrations for fire brigades and are derived for only one severity level - defined as no health hazard - and one exposure period (4 hours). The current version adopts AEGL-2 values as well and a total of 45 values are now included.

TEEL - Temporary Emergeny Exposure Limits

TEEL values, initiated by the Department of Energy, reflect three levels of severity with similar criteria as AEGL and one exposure period (60 minutes). They are used as preliminary guidance until in depth assessments are performed. There are no support documents.

IDLH - Immediately Dangerous to Life and Health

IDLH values, developed by OSHA and NIOSH, reflect only one level of severity (severe to life-threatening) and one exposure period (30 minutes). One of the main purposes is to provide guidance in the selection of protection equipment. A brief documentation of the values is available.

ARE - Acute Reference Exposure

In 1998, EPA published a draft report on the methodology to derive acute reference exposure values. While the primary goal is the derivation of a concentration or dose level without adverse effects, the proposed methodology also allows to establish effect concentrations for varying levels of severity ("Adverse Effect Level" (AEL1 and AEL2) and "Franc Effect Level" (FEL)). The criteria for these levels is different from the AEGL criteria, e.g. the ability to escape is not an AEL2- criterion in ARE methodology. Because ARE methodology employs sophisticated mathematical analysis (e.g. benchmark dose modelling and categorical regression) there is a need for a very good data base.

Short link: www.umweltbundesamt.de/n14644en