In order to reduce greenhouse gas emissions, cooling technologies based on natural refrigerants with negligible or insignificant effect on the environment and climate have experienced a renaissance in recent years. A variety of highly efficient applications has been developed and has now reached a technical level that makes their use economically viable. Because natural refrigerants require careful handling, particular attention has to be paid to adequate qualification of servicing personnel. This guidance document presents recommendations for the implementation of relevant EU legislation, which have been derived from experiences made in the training and certification system in Germany.