The subject of this project was the preparation of substance reports for five substances relevant for building products emissions. For these substances, the toxicological data basis were compiled and evaluated, and EU-LCI values were proposed. The EU-LCI values allow the harmonisation of the health assessment of building products emissions throughout Europe. The EU-LCI Working Group is currently developing a European list of substances and their associated emission limits. The substance reports developed within this project support and accelerate this process. The project outcome is relevant for all stakeholder involved in the topic of building products emissions.