Cover_TEXTE_167-2020_Validation of the NSAID in vitro assay for biomonitoring of NSAID activities in surface waters
Chemicals, Water

Validation of the NSAID in vitro assay for biomonitoring of NSAID activities in surface waters


The NSAID in vitro-Bioassay – originally developed for municipal waste water samples – can now be used to detect activity of cox-inhibitors in surface waters as well. By using 44 water samples from several European countries the application range and quality of this bioassay was increased and the limit of detection is further reduced to now 12 ng diclofenac/l. In this project other characteristics like linearity, recovery and accuracy of the test were determined as well. The improved bioassay version can be used as screening tool prior to an extensive chemical analysis. Furthermore, it can be used to avoid false negative assessment and under-estimation of environmental pollutions caused by usage chemical analysis methods only.

Series
Texte | 167/2020
Number of pages
43
Year of publication
Author(s)
Manfred Frey, Marco Scheurer
Language
English
Project No. (FKZ)
3717 63 440 0
Publisher
German Environment Agency
Additional information
PDF is accessible
File size
5404 KB
Price
0,00 €
Print version
not available
rated as helpful
43
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Tags:
 effect biomonitoring; in vitro; NSAID; cox inhibitors; human pharmaceuticals