Publikation:Comparative analysis of estimated and measured BCF data (OECD 305) - Literature study with a special focus on differential accumulation of (mixtures of) stereoisomers
Chemikalien

Comparative analysis of estimated and measured BCF data (OECD 305)

Literature study with a special focus on differential accumulation of (mixtures of) stereoisomers


Bioaccumulation potential of chemicals is frequently assessed from bioconcentration, conventionally measured according to OECD 305 (Bioaccumulation: Flow-through Fish Test) (OECD,1996) and expressed as Bioconcentration Factor (BCF). These studies deliberately reduce the manifold uptake and elimination mechanisms in aquatic organisms to respiratory absorption via gills and diffusion through the skin (e.g. Arnot and Gobas, 2003; Sijm et al. 2007). Despite the simplifications, testing costs are high and a minimum of 108 fish are consumed in each OECD 305 bioconcentration guideline study (ILSI HESI, 2006).

Reihe
Texte | 15/2011
Seitenzahl
59
Erscheinungsjahr
Autor(en)
Dr. Martin Müller, Dr. Monika Nendza
Sprache
Englisch
FKZ
360 04 024
Verlag
Umweltbundesamt
Dateigröße
3219 KB
Preis
0,00 €
Status
nicht lieferbar
Als hilfreich bewertet
15
Teilen:
Artikel:
Drucken Senden
Schlagworte:
 bioconcentration  bioconcentration factor  accumulation  QSAR  Stereoisomer